Drugs outperform ultrafiltration in acute cardiorenal syndrome
نویسندگان
چکیده
منابع مشابه
Reconsidering ultrafiltration in the acute cardiorenal syndrome.
Aggressive diuretic therapy in a patient who is hospitalized for acute decompensated heart failure often leads to progressive renal dysfunction despite persistent congestion. The underlying mechanisms of this so-called acute cardiorenal syndrome are complex and not fully understood.1,2 As initial therapy in this setting, ultrafiltration as compared with diuretic therapy may result in a higher r...
متن کاملUltrafiltration in decompensated heart failure with cardiorenal syndrome.
BACKGROUND Ultrafiltration is an alternative strategy to diuretic therapy for the treatment of patients with acute decompensated heart failure. Little is known about the efficacy and safety of ultrafiltration in patients with acute decompensated heart failure complicated by persistent congestion and worsened renal function. METHODS We randomly assigned a total of 188 patients with acute decom...
متن کاملPharmacologic diuresis is safer than ultrafiltration for cardiorenal syndrome
A critical appraisal and clinical application of Bart BA, Goldsmith SR, Lee KL, et al. Ultrafiltration in decompensated heart failure with cardiorenal syndrome. N. Engl. J. Med. 2012;367:2296-2304. doi: 10.1056/NEJMoa1210357
متن کاملCardiorenal syndrome: ultrafiltration therapy for heart failure--trials and tribulations.
Heart failure remains the leading cause of hospitalization in older patients and is considered a growing public health problem with a significant financial burden on the health care system. The suboptimal efficacy and safety profile of diuretic-based therapeutic regimens coupled with unsatisfactory results of the studies on novel pharmacologic agents have positioned ultrafiltration on the foref...
متن کاملCardiorenal Syndrome in Acute Heart Failure Syndromes
Impaired cardiac function leads to activation of the neurohumoral axis, sodium and water retention, congestion and ultimately impaired kidney function. This sequence of events has been termed the Cardiorenal Syndrome. This is different from the increase in cardiovascular complications which occur with primary kidney disease, that is, the so-called Renocardiac Syndrome. The present review discus...
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ژورنال
عنوان ژورنال: Nature Reviews Nephrology
سال: 2012
ISSN: 1759-5061,1759-507X
DOI: 10.1038/nrneph.2012.237